MRSA Bacteremia
Conditions
Brief summary
Staphylococcus aureus represents one of the most met germs, with Escherichia coli, during bacteremia. Microbiologist distinguish at aureus S. two profiles of resistance in beta-lactamines: S. aureus sensitive to the methicillin ( SASM) and the S. aureus resistant to the methicillin ( SARM). With the implementation of the MALDI-TOF, it is now possible to identify the origin responsible of the bacteremia the day of the positivity of the hemoculture ( J0) and to set up a treatment with adapted antibiotic, which, in the case of a sepsis to aureus S., is the vancomycine. Ye it was demonstrated, that the use of the vancomycine on the SASM increased the average duration of stay and a more important rate of relapse. The PCR SARM was organized in the GHPSJ in 2014. It allows from the day of the positivity of the hemoculture ( J0), to determine the phenotype of resistance of S. aureus.
Interventions
DIAGNOSTIC_TESTPolymerase Chain Reaction of Methicillin Resistant Staphyloccus Aureus
Polymerase Chain Reaction of Methicillin Resistant Staphyloccus Aureus
Sponsors
Fondation Hôpital Saint-Joseph
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Hemoculture positive to Staphylococcus Aureus Methicillin Sensitive
Exclusion criteria
* Positive test to Staphylococcus Aureus Methicillin Sensitive but not hospitalized.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Adaptation duration of antibiotherapy | 24 hours |
Secondary
| Measure | Time frame |
|---|---|
| Mortality | Day 30 |
| average duration of hospitalization | day 30 |
Countries
France
Outcome results
None listed