Apnea
Conditions
Keywords
dynamic apnea, muscle oxygenation, physical performance
Brief summary
The inclusion of short periods of apnea (several seconds) during exercise (i.e. dynamic apnea) induces a significant decrease in blood oxygenation and muscle tissue. To date, the immediate effects (acute apnea) of this decrease in the quantity of oxygen available at the muscle and brain level are poorly understood. Moreover, a physical training during which these short periods of apnea (chronic apnea) would be included could lead to physiological adaptations and to improvement in physical performance similar to those obtained during altitude training. The purpose of this study is to evaluate the effects of acute dynamic apnea on metabolism.
Interventions
OTHERProgram of training with exercises including apnea
16 training session on cycle ergometry with exercises including apneas.
OTHERProgram of training with exercises without apnea
16 training session on cycle ergometry with exercises without apnea
Sponsors
Laboratoire de Complexité, Innovation et Activités Motrices et Sportives
Centre Hospitalier Régional d'Orléans
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* The cutaneous thickness at the vastus lateralis level lower than 1.5 cm to obtain the reliable muscle oxygenation measurement * Subjects will have to sign the inform consent before the beginning of the study
Exclusion criteria
* Contraindications to regular physical exercise practice * To practice an endurance sport more than 1h/week * Regular practice of apnea * Chronic use of cannabis and/or alcohol * Cardiac or metabolic pathology * Asthma and/or bronchodilatator treatment * ECG abnormality at rest * Regular consumption of tobacco
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Spectometry to measure hemoglobin | 12 weeks | Measurement of oxygenation |
| Jaeger debimeter system to measure of peak oxygen | 3 weeks | Measurement of oxygen consumptiom |
| Measurement of arterial saturation in dioxygen | 3 weeks | Measurement by ear blood micro-sample |
| Spectometry to measure hemoglobin rate | 3 weeks | Measurement of oxygenation |
| Wingate test to measure maximum consumption of dioxygen | 3 weeks | Measurement of aerobic performance |
| Measurement of hormonal markers | 3 weeks | Measurement of Dehydroepiandrostenedione (DHEA) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Borg scale to measure penibility of the effort | week 3 | — |
| Cardiac frequency | 3 weeks | measurement with a 12 lead - Electrocardiogamm |
Countries
France
Outcome results
None listed