Vitamin A and Azithromycin for Acne Vulgaris

Treatment of Acne for Cases Resistant to Currently Available Measures Via Vitamin A With or Without Azithromycin in Topical Formulations

Status

UNKNOWN

Phases

Early Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03090048

Enrollment

Registered

2017-03-24

Start date

2021-04-01

Completion date

2021-10-31

Last updated

2021-02-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne Vulgaris

Brief summary

Patients seen with acne lesions not having responded to existing treatments will be offered a placebo or a topical preparation consisting of Vitamin A USP with or without Azithromycin for a duration of 4-6 months USP for the objective of resolving the lesions without systemic side effects and via weekly follow-ups.

Detailed description

The concentrations of the active ingredients is based on the enclosed articles and the formulations have been modified with an objective of minimizing the side effects.

Interventions

DRUGVitamin A

Vitamin A 2-3 % concentration

DRUGAzithromycin

azithromycin monohydrate

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Investigator)

Eligibility

Sex/Gender

ALL

Age

12 Years to 45 Years

Healthy volunteers

Yes

Inclusion criteria

* Patients with active lesions

Exclusion criteria

* Patients on a treatment * Asymptomatic patients

Design outcomes

Primary

Measure	Time frame	Description
Measurement (dimensions) of acne lesions	Every 4 weeks up to16 weeks	follow-up focussed on observation of changes

Countries

Canada

Contacts

Primary ContactVinod C Tawar, M.Sc., M.D.

Tawar.vinod@yahoo.com604 754 2235

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026