Atherosclerosis, Metabolic Syndrome
Conditions
Brief summary
The effects of 12 hours of prolonged standing will be compared to prolonged standing on a high fat tolerance test the following day. Plasma triglycerides, insulin, and glucose will be measured in a crossover study design.
Interventions
BEHAVIORALProlonged Standing
Subject will stand for 12 hours and undergo a high fat tolerance test the subsequent day
BEHAVIORALProlonged Sitting
Subject will sit for 12 hours and undergo a high fat tolerance test the subsequent day
Sponsors
University of Texas at Austin
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
\-
Exclusion criteria
* heart problems * coronary artery disease * hypertension * respiratory problems * musculoskeletal problems that prevent prolonged standing or sitting * obesity * susceptibility to fainting
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Plasma Triglycerides | 6 hours | The area under the curve for plasma triglycerides from hourly samples during a 6 hour high fat tolerance test |
| Plasma Insulin | 6 hours | The area under the curve for plasma insulin from hourly samples during a 6 hour high fat tolerance test |
| Plasma Glucose | 6 hours | The area under the curve for plasma glucose from hourly samples during a 6 hour high fat tolerance test |
Countries
United States
Outcome results
None listed