The Effect of Intraabdominal Saline Irrigation in Abdominal Hysterectomies

The Effect of Intraabdominal Saline Irrigation on Infectious Morbidities and Gastrointestinal Outcomes in Patients Undergoing Abdominal Hysterectomies for Benign Causes

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03085732

Enrollment

100

Registered

2017-03-21

Start date

2017-02-01

Completion date

2017-06-30

Last updated

2017-03-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecologic Surgery

Keywords

saline irrigation, abdominal hysterectomy, postoperative infectious morbidities, gastrointestinal disturbances

Brief summary

The objective of this prospective randomised clinic study is to investigate the effect of peritoneal cavity saline irrigation during abdominal hysterectomies on postoperative infectious morbidities and gastrointestinal disturbance. The participants will be randomised to either an irrigation of abdominal cavity or the control group after vaginal closure. Assignment to one of the two treatment groups will be determined using a computer generated random numbers. Primary outcome is the rate of postoperative infectious morbidities. Secondary outcome is the rate of gastrointestinal disturbances (nausea, vomiting), use of antiemetic drugs and pain score in the postoperative period. 100 patients in each treatment arm planned.

Interventions

DRUGIrrigation with Saline Solution

During hysterectomy after vaginal cuff closure 500-1000 mL saline irrigation will be done.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

40 Years to 65 Years

Healthy volunteers

Inclusion criteria

* patients undergoing hysterectomies for benign causes

Exclusion criteria

* patients who have diabetes mellitus patients undergoing hysterectomy for pelvic inflammatory disease or tuboovarian abscess

Design outcomes

Primary

Measure	Time frame	Description
postoperative infectious morbidities	10 day after hysterectomy operation	vaginal cuff infection diagnosed with vagen cuff culture

Secondary

Measure	Time frame	Description
gastrointestinal outcomes: nausea by questionnaire	postoperative first day	nausea by questionnaire
gastrointestinal outcome: vomiting by questionnaire	postoperative first day	vomiting by questionnaire

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026