Hematoma, Intracerebral Hemorrhage, Stroke
Conditions
Keywords
intracerebral hemrrohage, stroke, China, hematoma, CT, predictor, prognosis, outcome
Brief summary
The Chongqing intracerebral hemorrhage study is a multi-center, prospective, observational study led by professor Qi Li from Chongqing Medical University. Professor Peng Xie will be the senior consultant for the study. The Chongqing intracerebral hemorrhage study will focus on the epidemiology, natural history, pathogenesis, laboratory, radiological aspects, clinical outcomes and the effects of treatment in patients with intracerebral hemorrhage. The clinical, laboratory, imaging, genetic and outcome data of patients diagnosed with acute intracerebral hemorrhage will be prospectively collected. The prognosis of patients with intracerebral hemorrhage will be assessed by using several outcome measure scales at different time points.
Detailed description
The Chongqing intracerebral hemorrhage study will try to address several key issues in ICH. The baseline clinical data including demographic, disease severity scores, prior drug history and relevant medical history, premorbid mRS scores will be prospectively recorded. The admission and follow-up imaging data of all registered patients will be saved as Dicom format for future use and review. The functional outcomes will be assessed and recorded by experienced neurologists.
Interventions
None listed
Sponsors
First Affiliated Hospital of Chongqing Medical University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age \>= 18 years * Informed consent to participate in the study * Patients diagnosed with CT-confirmed spontaneous Intracerebral Hemorrhage (ICH) * Patients are willing to participate in the follow up assessment
Exclusion criteria
* Did not agree to participate in the study * Secondary ICH to hemorrhagic infarction or tumor bleeding etc. * Traumatic ICH
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| hematoma volume growth at 24 hours | 24 hours | To assess early hematoma volume growth at 24 hours |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| early neurological deterioration assessed by NIHSS score at 24 hours | 24 hours | To assess early neurological deterioration using NIHSS score at 24 hours |
| early neurological deterioration assessed by NIHSS at 48 hours | 48 hours | To assess early neurological deterioration using NIHSS score at 48 hours |
| early neurological deterioration assessed by NIHSS score | 72hours | To assess early neurological deterioration using NIHSS score at 72 hours |
| functional outcome at 3 months assessed by modified Ranking Scale | 3 months | assess functional outcome at 3months using mRS |
| perihematoma edema volume measurement at 72 hours | 72 hours | to measure the perihematoma edema volume at 72 hours |
| intraventricular hemorrhage growth | 24 hours | to assess the presence of IVH at 24 hours |
| major thromboembolic events | 2 weeks | to assess the thromboembolic events 2 weeks after admission |
| perihematoma edema volume measurement at 24 hours | 24 hours | to measure the perihematoma edema volume at 24 hours |
Countries
China
Contacts
Primary ContactQi Li, MD;PhD
Outcome results
None listed