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Executive Training and Brain in Adolescent

Cerebral Bases of the Cognitive Learning in the Executive Control In the Adolescence

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03084848
Acronym
APEX-ADO
Enrollment
60
Registered
2017-03-21
Start date
2016-05-18
Completion date
2017-12-31
Last updated
2019-07-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

brain/cognitive measures, condition, inhibitor control, training at adolescence

Brief summary

The purpose of this study is to investigate the cognitive and brain effects of inhibitory control (IC) training at adolescence.

Detailed description

Brain imaging now allows to study non-invasively cognitive learning processes. An area of strong scientific interest is the development of executive control, an essential cognitive domain for academic and professional success and for mental and physical health. These functions are essentially located within the prefrontal cortex, characterising by a late maturation until the end of adolescence and, while under genetic control, can likely be improved with targeted interventions. The objective of this project is simple and innovative: testing in adolescents with the most appropriate brain imaging technologies available today (the Magnetic Resonance Imaging, MRI), the effect of an executive training focused on the inhibitory control (IC). This project aims at precisely testing the effect at the cognitive and brain levels of IC training in adolescence. To do this, the investigators will recruit two groups of 30 teenagers aged 16 to 17 years old, each assigned to one of two learning situations: IC vs Active Control (AC). Each participant will participate in 25 training sessions of 15 minutes per day, 5 days a week for a month. Brain structural and functional differences in the brain and between the pre-test and post-test related to intense IC training will be correlated with cognitive progress.

Interventions

OTHERTraining

25 training sessions of 15 minutes per day, 5 days a week for a month of crystallised intelligence

Sponsors

Centre National de la Recherche Scientifique, France
CollaboratorOTHER
Centre Hospitalier St Anne
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
16 Years to 17 Years
Healthy volunteers
Yes

Inclusion criteria

* 16-17 years old * girl or boy ; * French mother tongue; * Handedness: Right; * Schooled in a level corresponding to its age (2nd or 1st) * Informed consent signed by the (s) holder (s) of parental authority, in agreement with the teenager * Normal medical, neurological, neuroradiological examinations. * Health insurance

Exclusion criteria

* classical

Design outcomes

Primary

MeasureTime frame
Brain plasticity : Longitudinal cortical thickness changeBaseline

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026