Low Dose Computed Tomography for Lung Cancer Screening

Smoking Cessation in Lung Cancer Screening: Integrated Digital/Clinical Approach

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03084835

Acronym

LDCT

Enrollment

Registered

2017-03-21

Start date

2017-08-14

Completion date

2019-04-30

Last updated

2019-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Smoking

Keywords

tobacco, smoking, low dose computed tomography, lung screening, text messaging

Brief summary

This study will evaluate the impact of a proactive, EHR-supported enrollment strategy that links LDCT-eligible smokers with an evidence-based intervention comprised of a web-based program and integrated text messaging. The goal is to provide actionable findings about how to most effectively and cost efficiently promote abstinence in LDCT clinics.

Detailed description

Using a 3-arm randomized trial design with repeated measures at 1, 3, 6, and 12 months, the study will randomize N=1650 smokers who present for LDCT lung cancer screening to an passive referral usual care control condition, proactive referral to a digital cessation intervention that combines web and text messaging, or proactive referral to a digital cessation intervention combined with Tobacco Treatment Specialist counseling. The Study will examine overall effectiveness of the interventions in promoting abstinence, the impact of proactive referral to treatment, and the total cost and cost effectiveness of the interventions. The Study will also examine the representativeness of the enrolled sample and explore barriers and facilitators to intervention adoption with LDCT clinic leaders. The trial is structured as a practical clinical trial to answer key questions of direct relevance to LDCT decision-makers.

Interventions

BEHAVIORALUsual Care

Brief cessation counseling

BEHAVIORALWEB+TXT

Access to Become an Ex website plus text messaging

BEHAVIORALWEB+TXT+TTS

Access to Become an Ex website plus text messaging plus consult with a trained tobacco treatment specialist

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

1. Scheduled for LDCT screening 2. Current smoking (every day/some days) 3. At least weekly use of the Internet 4. Current ownership of cell phone with a text messaging plan 5. Willing to receive study text messages. 6. Ability to complete all aspects of the study 7. Ability to provide signed informed consent

Exclusion criteria

1. Current (in the past 30 days) use of tobacco cessation medication or participation in tobacco cessation treatment. 2. Those with a condition deemed by the investigators to be exclusionary to the study

Design outcomes

Primary

Measure	Time frame	Description
smoking abstinence	12 months	biochemically confirmed 12 month smoking abstinence of WEB+TXT;

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 25, 2026