Peripheral Nerve Injuries
Conditions
Brief summary
The study examines pain-related evoked potentials (PREP) in patients with peripheral nerve injuries. Since previous studies found altered latencies and amplitudes of PREP in generalized polyneuropathies, e. g. HIV-polyneuropathy and fibromyalgia, this study investigates if these alterations are detectable in unilateral peripheral nerve injuries as well.
Interventions
DIAGNOSTIC_TESTPain-related evoked potentials (PREP)
PREP were performed bilaterally with a concentric surface electrode at twice the individual pain threshold.
DIAGNOSTIC_TESTQuantitative Sensory Testing (QST)
QST was performed bilaterally following the protocol of the German Network on Neuropathic Pain.
DIAGNOSTIC_TESTNerve conduction studies (NCS)
NCS were performed with patients only.
Sponsors
Ruhr University of Bochum
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
* Peripheral Nerve Injury
Exclusion criteria
* Polyneuropathy * Contralateral peripheral nerve injury * Severe psychiatric disorders * Disorders affecting central nervous system
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| N1-latency | 1 day | N1-latency of pain-related evoked potentials in ms |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| N1P1-amplitude | 1 day | Amplitude of pain-related evoked potentials in µV |
Outcome results
None listed