The CCUS Based Characteristic of Hemodynamic and Lung Pathology in Early Stage of Shock in ICU: The Epidemic and Prognostic Value

The Critical Care Ultrasound Based Characteristic of Hemodynamic and Lung Pathology in Early Stage of Shock in ICU: The Epidemic and Prognostic Value

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03082326

Enrollment

181

Registered

2017-03-17

Start date

2016-04-05

Completion date

2017-06-06

Last updated

2017-08-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shock

Keywords

shock, critical care ultrasound, hemodynamics, lung pathology, epidemic, prognosis

Brief summary

Shock is a common condition in critical care unit (ICU). It is extremely important that the patient accepts early goal-directed therapy (EGDT) treatment in the early stage of shock. However, several studies failed to demonstrate that the well used variables such as CVP and others could direct to a better treatment. In recent years, critical care ultrasound (CCUS) has been respected as a reliable noninvasive tool and widely used in ICU practice. With CCUS the investigators can accurately acquired the detailed information of the characteristic of the hemodynamics and lung pathology (the systole and diastole function, volume status, valve insufficiency, lung, edema, consolidation, and pleural effusion, etc.). To the investigators knowledge, there is no study investigating the epidemic of such ultrasonic variables and its value to predict to outcome. The aim of this study is to investigate the epidemic and the prognostic value of CCUS Based Characteristic of Hemodynamic and Lung pathology in Early Stage of Shock in patients admitted in ICU.

Detailed description

Adult patients who admitted to the intensive care unit of West China hospital of sichuan university with shock from April 2016 to April 2017 enrolled.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. SBP\<90 mm Hg or MAP \<70 mm Hg or SBP decrease \>40mmHg or need vasoactive drugs; 2. Skin that is cold and clammy, capillary refill time \>4.5s, urine output of \<0.5ml/Kg.hr and lactate\>2mmol/L; 3. SHOCK presented within 6 hr.

Exclusion criteria

1. \<18 years old; 2. Pregnancy; 3. Patient or family member refuse to be enrolled.

Design outcomes

Primary

Measure	Time frame
all cause mortality	28 days

Secondary

Measure	Time frame
length of mechanical ventilation	through study completion, an average of 28 days
ICU length of stay	through study completion, an average of 28 days
hospital length of stay	through study completion, an average of 28 days

Countries

China

Outcome results