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Quantitative Sensory Testing in Subjects With Sensitive Skin or Not

Quantitative Sensory Testing in Subjects With Sensitive Skin or Not

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03081403
Acronym
SENSISKIN
Enrollment
42
Registered
2017-03-16
Start date
2017-04-14
Completion date
2017-10-27
Last updated
2025-02-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sensitive Skin

Keywords

Sensitive skin, Quantitative Sensory Testing

Brief summary

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin. The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers. The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Detailed description

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin. A sensitive skin is characterized by the occurrence of tingling sensations, tightness, heat, burning, itching or pain triggered by non pathogenic factors such as wind, heat, cold, water , cosmetics, toiletries, stress... The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers. The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Interventions

DEVICEQuantitative Sensory Testing

Study of detection thresholds of vibration, cold and pain related to the heat in the dominant hand of the subjects through the QST.

Sponsors

University Hospital, Brest
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* Age: between 20 and 60 years * Cooperating patient * Informed and written consent of the subject * Affiliated to the social security * For subjects with sensitive skin: subjects with a score greater than 50 on the scale sensitive scale \- To control subjects: subjects with result of less than 20 sensitive to the scale scale

Exclusion criteria

* Adults subject with legal protection * Subject in a social institution. * Subject with major cognitive or psychiatric disorders * Subject with pathological use of alcohol or consumption of another drug. * Subject with skin involvement of the back of the dominant hand or malformation. * Known sensitive neuropathy * Pregnant woman * Subject receiving medical treatment which may interfere with the results. * Subject with treatment in the back of the dominant hand.

Design outcomes

Primary

MeasureTime frameDescription
Cutaneous perception threshold6 monthsThe cutaneous perception threshold of pain to heat.

Secondary

MeasureTime frameDescription
The cutaneous perception threshold of vibration6 monthsThe cutaneous perception threshold of pain to harm.
The cutaneous perception threshold of cold6 monthsThe cutaneous perception threshold of cold

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026