Effect of 12 Weeks of Acupuncture on AMH and COH in Low Responder Patients

Effect of 12 Weeks of Acupuncture on AMH and Ovarian Reserve in Women With Low Ovarian Reserve. A Pilot Study

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03080584

Enrollment

Registered

2017-03-15

Start date

2016-11-12

Completion date

2018-06-30

Last updated

2017-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female Infertility, Hypogonadism; Ovarian

Keywords

acupuncture, IVF, AMH, ovarian reserve

Brief summary

the investigators want to study whether 12 weeks of acupuncture has any effect on AMH and the ovarian reserve in women with low ovarian reserve (low responders). AMH is measured before and after 12 weeks of acupuncture and the clinical response to controlled ovarian hyperstimulation before and after the acupuncture is compared.

Detailed description

AMH is measured cycle day 2 or 3 before and after 12 weeks of acupuncture and the levels are compared. Furthermore, secondary outcomes from IVF treatments before and after the intervention are compared.

Interventions

OTHERacupuncture

12 weeks of acupuncture comprising basic acupuncture, ear acupuncture and Moving cups. On top of the basic acupuncture, additional locations can be added.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Masking

NONE

Intervention model description

comparison of AMH and ovarian response before and after acupuncture

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 40 Years

Healthy volunteers

Inclusion criteria

* IVF/ICSI treatment * 18-40 years * AMH measured \< or = 10 pmol/l * maximum of 8 oocytes collected at last treatment before inclusion-

Exclusion criteria

* (use of testicular sperm) * more than 4 acupuncture treatments within the last 3 months before inclusion -

Design outcomes

Primary

Measure	Time frame	Description
AMH	chance from baseline after 12 weeks of acupuncture	anti-Müllerian Hormone level

Secondary

Measure	Time frame	Description
No. of oocytes aspirated	change from baseline treatment and after 12 weeks of acupunture	the number of oocytes collected during egg aspiration for IVF
FSH dose/oocyte collected	change from baseline treatment and after 12 weeks of acupuncture	—
TQE 44 hours after fertilisation	change from baseline treatment and after 12 weeks of acupuncture	The number of top quality embryos 44 hours after fertilisation
biobank with blood plasma	2 years after treatment completion	—

Countries

Denmark

Contacts

Primary ContactUrsula Bentin-Ley, M.D.

ursula@danfert.dk+45 3834 9030

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026