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The Prenatal/Early Infancy Project: An Adolescent Follow-up

The Prenatal/Early Infancy Project: An Adolescent Follow-up

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03079752
Enrollment
629
Registered
2017-03-14
Start date
1994-03-18
Completion date
1998-04-30
Last updated
2017-03-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Behavior, Adaptive

Brief summary

The Nurse-Family Partnership, a program of prenatal and infancy home visiting by nurses, has been examined in a series of 3 randomized trials since 1977. It has received considerable attention in the scientific and public policy communities for its replicated effects on a variety of maternal and child health outcomes across these 3 trials, including prenatal health, childhood injuries, rates of subsequent pregnancies, inter-birth intervals, as well as its long-term effects on maternal life-course, criminal behavior, and 15-year-olds' criminal and antisocial behavior in the first trial of the program conducted in Elmira, New York.

Detailed description

Although this program produced positive effects on maternal and child health from pregnancy through the child's fourth year of life, its long-term effects remain unexamined. The current study was conducted to determine the extent to which the beneficial effects of the program set in motion early in the life cycle altered the life-course trajectories of the mothers and the children's adaptive functioning through the first child's 15th birthday. This study examines the long-term effects of the program on two domains of maternal functioning: 1) maternal life course (subsequent children, use of welfare, employment, substance abuse, and encounters with the criminal justice system); and 2) perpetration of child abuse and neglect; and two domains of the children's behavior: 1) their functioning in schools, and 2) their criminal and antisocial behavior. The investigators hypothesized that the program effects in these domains of maternal and child functioning, as in earlier phases of the study, would be greater for families in which the mothers experienced a larger number of chronic stressors and had fewer resources to manage the challenges of living in poverty and being a parent.

Interventions

Child participants were screened for sensory and developmental problems and referred for further evaluation and treatment of suspected problems at 12 and 24 months of age

Child participants were screened for sensory and developmental problems and referred for further evaluation and treatment for suspected problems at 12 and 24 months of age; their mothers were provided with free transportation for prenatal and well-child care through child age 2.

Child participants were screened for sensory and developmental problems and referred for further evaluation and treatment for suspected problems at 12 and 24 months of age; their mothers were provided with free transportation for prenatal and well-child care through child age 2, and were provided an average of 9 home visits by nurses during pregnancy.

Child participants were screened for sensory and developmental problems and referred for further evaluation and treatment for suspected problems at 12 and 24 months of age; their mothers were provided with free transportation for prenatal and well-child care through child age 2, and were provided an average of 9 home visits by nurses during pregnancy and 23 during the child's first two years of life.

Sponsors

Cornell University
CollaboratorOTHER
University of Colorado, Denver
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)

Masking description

Assessors were not given access to the participants' original treatment assignments

Eligibility

Sex/Gender
ALL
Age
15 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Must be offspring of mothers who enrolled in Elmira randomized clinical trial of the Nurse-Family Partnership (known as the Prenatal Early Infancy Project) -

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
Timing of Subsequent Births - Mothers15 years following birth of first childInterval in days between birth date of first child and first subsequent child (self-reported)
Months Received Aid to Families with Dependent Children (AFDC) - Mothers15-year interval following birth of first childNumber of months mother received AFDC (self-reported)
Number of Months Employed - Mothers15-year interval following birth of first childNumber of months employed (self-reported)
Substance Abuse - Mothers15-year period following birth of first childCount of behavioral impairments due to use of substances (self-reported)
Arrests - Mothers15-year interval following birth of first childCount of arrests (self-reported)
Child Maltreatment Reports - Mothers15-year interval following birth of first childCount of substantiated reports of child abuse and neglect in which mother was perpetrator (review of records)
Running Away from Home - Children15-year interval following birth of first childCount of times ran away from home - self-report
Person in Need of Supervision (PIN) - Children15-year period following their birthSelf report of ever having been adjudicated as a PIN
Arrests - Children15-year period following birthCount of Arrests - self-report

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026