Dry Eye
Conditions
Brief summary
To evaluate the short term effects of LACRISERT®. upon fluorescein corneal staining, tear osmolarity and surface topography in human subjects with dry eye disease.
Interventions
DRUGLacrisert, 5 Mg Ophthalmic Insert
Sponsors
Virginia Eye Consultants
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
-Has Dry Eye disease indicated by a staining score of ≥ 4 and Speed score of \>6
Exclusion criteria
* Concurrent involvement in any other clinical trial * Anticipated contact lens wear during the study and 14hours prior to Day -History of corneal transplant * Active ocular infection, uveitis or non-KCS inflammation * History of recurrent herpes keratitis or active disease within the last six months * Topical ophthalmic medications during the study * Temporary collagen punctal plugs within one week prior to study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dry Eye disease measured by OSDI questionnaire | 10 days |
| Dry eye disease measured by Corneal Staining | 10 days |
| Dry eye disease measured by topographic results | 10 days |
Countries
United States
Contacts
Primary ContactJireh A
Outcome results
None listed