Iodine Deficiency, Pregnancy Related
Conditions
Brief summary
Pregnant women who attend at our antenatal clinic will random to 2 groups. First will receive routine iodine supplementation. The other will receive iodinated pill or only iron supplementation base on their urine iodine status.
Interventions
DIETARY_SUPPLEMENTTriferdine
Triferdine 1 tablet daily Start from 14 weeks of gestation until delivery
DIETARY_SUPPLEMENTTriferdine/Ferli-6
For the participants assigned to this group, urine iodine level will be checked first. For participants with normal urine iodine level, Ferli-6 1 tab daily will be given. For those with low urine iodine level, Triferdine 1 tab daily will be given. Medication will be started from 14 weeks of gestation until delivery.
Sponsors
Chiang Mai University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
* first visit for antenatal care in the first trimester * singleton pregnancy * delivered at Maharaj Nakorn Chiangmai Hospital
Exclusion criteria
* thyroid disease which diagnosed before pregnancy or currently * history of thyroid gland surgery or iodine ablation therapy * received iodine supplement before pregnancy * received any medication for thyroid disease treatment, within 6 weeks postpartum women or breast feeding period * family history of thyroid disease * having underlying disease or contraindication which cannot received iodine supplement * loss follow-up or incomplete data.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| iodine status | at delivery | mean urine iodine |
Countries
Thailand
Outcome results
None listed