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Capnography in the Post-Anesthesia Care Unit (PACU)

Preliminary Characterization of the Capnography Profile of Obstructive Sleep Apnea (OSA) Patients in the Post-Anesthesia Care Unit (PACU)

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03076047
Enrollment
100
Registered
2017-03-09
Start date
2017-11-06
Completion date
2023-02-09
Last updated
2022-06-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bariatric Surgery Candidate, Obstructive Sleep Apnea, Respiratory Insufficiency

Brief summary

To understand if a progressive increase in end-tidal carbon dioxide (CO2) levels are heralding respiratory difficulties before desaturation measured from capnography in obstructive sleep apnea patients, with the use of nasal prongs, transcutaneous monitors, Capnostream, and Massimo technologies.

Detailed description

Background and Significance Carbon dioxide (CO2) levels can be monitored throughout the respiratory cycle via capnography. In this way, capnography allows healthcare professionals to follow a number of respiratory factors (i.e., depression, apnea, and hypercapnia) in real-time. Earlier detection of alterations to ventilation status will better enable providers to more accurately dose medications during procedures, especially in at-risk patient populations such as patients with obstructive sleep apnea (OSA) \[1, 2\]. In a recent study of bariatric patients, approximately 15% experience postoperative pulmonary complications. These patients could benefit significantly from capnography monitoring as this measure can very accurately estimate the prevalence of respiratory complications. Through this study we seek to understand how end-tidal CO2 (ETCO2) levels of patients with obstructive sleep apnea vary when patients are in the post-anesthesia care unit (PACU). By collecting information on patient outcomes, we hope to better understand the value of this monitoring technique in an at-risk patient population. Though capnography in the PACU has not previously been demonstrated to improve patient safety or satisfaction, capnography has never been studied in a population of patients who are at risk of obstructive sleep apnea. Study Design This is a prospective, blinded observational pilot study to monitor if changes in end-tidal CO2 levels provide incremental value over pulse oximetry when detecting respiratory difficulties (i.e., hypercapnia).

Interventions

DEVICEend-tidal CO2 (ETCO2) monitoring

monitor end tidal CO2 levels while patients recover in post-anesthesia care unit (PACU) using the Smart CapnoLine Plus O2, Capnostream, and Massimo

Sponsors

Medtronic - MITG
CollaboratorINDUSTRY
University of South Florida
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* \> 18 years of age * Patients who have are at TGH for bariatric surgery * BMI \> 30 * At risk of obstructive sleep apnea according to TGH STOP-BANG questionnaire

Exclusion criteria

* \<18 years of age * Not at risk of obstructive sleep apnea according to TGH STOP-BANG questionnaire

Design outcomes

Primary

MeasureTime frameDescription
end-tidal carbon dioxide (ETCO2)2-3 hoursend-tidal carbon dioxide (ETCO2) values averaged over 5 minute intervals

Secondary

MeasureTime frameDescription
oxygen saturation (SPO2)2-3 hoursoxygen saturation (SPO2) values from pulse oximetry

Countries

United States

Contacts

Primary ContactEnrico Camporesi, MD
ecampore@health.usf.edu813-844-4434

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026