Effect of Benzydamine Hydrochloride to Postoperative Sore Throat in Pediatric Patients

Effect of Benzydamine Hydrochloride to Postoperative Sore Throat in Pediatric Patients: a Randomized Controlled Trial

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03074968

Enrollment

142

Registered

2017-03-09

Start date

2017-03-08

Completion date

2018-04-05

Last updated

2018-04-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intubation Complication

Brief summary

This study is designed to examine the effect of benzydamine hydrochloride to postoperative sore throat in pediatric patients. We will spray benzydmaine hydrochloride or normal saline at oral cavity and the tip of endotracheal tube, than compare the prevalence of postoperative sore throat using smartphone application in pediatric patients.

Detailed description

1. postoperative sore throat incidence (over 2) 1; no, 2;mild, 3;moderate, 4;severe 2. scoring of pain with smartphone application (kids pain scale) 3. incidence of use of rescue pain killer

Interventions

DRUGBenzydamine Hydrochloride

Benzydamine Hydrochloride application

DRUGNormal saline

normal saline application

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

6 Years to 18 Years

Healthy volunteers

Inclusion criteria

* general anesthesia * intubation require

Exclusion criteria

* recent upper airway infection * could not express the pain

Design outcomes

Primary

Measure	Time frame	Description
pain	30 minutes in postanesthetic care unit	application based pain score

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 20, 2026