Insecticide Resistance Management in Burkina Faso and Côte D'Ivoire

Insecticide Resistance Management in Burkina Faso and Côte D'Ivoire: Research on Vector Control Strategies

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03074435

Acronym

REACT

Enrollment

15776

Registered

2017-03-08

Start date

2016-07-31

Completion date

2018-08-31

Last updated

2024-10-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malaria

Keywords

Randomized Controlled Trials

Brief summary

This study evaluates the benefit to use 1) insecticide residual sprayings, 2) larvicides, 3) Ivermectin for domestic animals and 4) behaviour change communication strategy to complement the universal coverage with LLINs through a cluster randomized trial.

Interventions

DEVICEIndoor residual sprayings

Houses will be spayed with this formulation containing Pyrimiphos methyl.

DEVICELarvicide

Larval breeding sites will be treated with larvicide

BEHAVIORALBCC

BIOLOGICALIvermectin

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Intervention model description

This is a cluster-randomized, parallel with baseline, trial. The study is bi-centric for the evaluation of two arms (LLIN+IRS and LLIN+BCC)

Eligibility

Sex/Gender

ALL

Age

No minimum to 21 Years

Healthy volunteers

Yes

Inclusion criteria

For Cross-sectional surveys only, maximum age for participating in the study was 21 y/o in Côte d Ivoire and 18 y/o in Burkina Faso.

Design outcomes

Primary

Measure	Time frame	Description
Malaria incidence density	continuous monitoring during 2 years	Malaria cases (whole population, every ages) registered in the local health system.

Secondary

Measure	Time frame	Description
Entomological Inoculation Rate	Every 8 weeks during 2 years	Number of infectious bites/personn
Malaria prevalence	Every 4 months during 2 years	% of positive blood smears among the 0-18 y/o population as recorded during cross sectional surveys.

Countries

Burkina Faso, Côte d’Ivoire

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026