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Prevalence of Oral Findings in Chronic Kidney Disease

Prevalence of Oral Findings in Adult Patients With Chronic Kidney Disease Cross Sectional

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03074188
Enrollment
225
Registered
2017-03-08
Start date
Unknown
Completion date
Unknown
Last updated
2017-03-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Diseases, Oral Disease

Keywords

oral findings or oral manifestation, pre-dialysis stage or end stage renal disease

Brief summary

There are severe deficiency of database concerning the oral health status in both pre-dialysis and end stage renal disease in Egyptian population. Our aim in the present study is to assess the oral health of the chronic kidney disease patients to increase their awareness and minimize all the possible risk factors, to achieve a proper management for all oral problems.

Detailed description

The study will be held in the Nephrology units at the Kasr Al-Ainy Cairo university hospital. The data collected through the questionnaire will be obtained through an interview between the investigator and the patient. Clinical examination will be performed for both oral (soft tissue) and dental (hard) tissue. For patients undergoing dialysis, examination will be performed before dialysis therapy. Selection bias: will be minimized by enrolling the participants in the study in a consecutive order of the entering the clinic. Non-respondent bias: will be minimized by explaining to the participants the aim of the study and their importance and role in the study. Incomplete records: will be excluded from statistical analysis with reporting the cause of not completing the record. Sample size estimation: Using a precision of 5, a design effect set at 1 with 90% CI (confidence interval), a total sample size of 250 pre-dialysis patients and 200 end stage renal disease patients will be sufficient. The sample size was calculated by Epi info software. The sample will be divided between two researchers; each researcher will have 50% of the whole sample to collect.

Interventions

None listed

Sponsors

Cairo University
CollaboratorOTHER
Alaa Mostafa Hassan Elnaggar
Lead SponsorOTHER

Study design

Observational model
ECOLOGIC_OR_COMMUNITY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

1. Adult patients \>18 years old with a diagnosis of non-dialysis chronic kidney disease at stage 2, 3 and 4. 2. Adult patients \>18 years old with a diagnosis of end stage renal disease stage 5. 3. Recorded data of Glomerular Filtration Rate for every patient. 4. Recorded data for dialysis patients (HCV, platelets count, creatinine, blood urea nitrogen, urea level and partial thromboplastin time).

Exclusion criteria

1. Adult patients \<18 years. 2. End stage renal disease undergoing peritoneal dialysis. 3. Patients not physically able to participate in oral examination. 4. Patients with kidney transplantation. 5. Patients undergoing renal dialysis for reasons other than chronic kidney disease, such as acute renal failure, accidents, trauma, snake poisoning.

Design outcomes

Primary

MeasureTime frameDescription
oral mucosal lesion10 minutesClinical examination according to WHO guidelines

Secondary

MeasureTime frameDescription
.Periodontal condition10 minutesBasic periodontal examination
Hepatitis C Virus at dialysis stage5 minutesHCV antibodies in patient blood

Contacts

Primary Contactalaa elnaggar, BDS
alaa_hassan@dentistry.cu.edu.eg01007802767
Backup ContactGihane Madkour
gihanemadkour@gmail.com01121001005

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026