Evaluation of the Risk of VTE Among Patients Hospitalized in Non-surgical Departments

The Risk for VTE Among Patients in the Medical Wards - Prospective Observational Study.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03073915

Enrollment

4000

Registered

2017-03-08

Start date

2013-08-31

Completion date

2020-12-31

Last updated

2018-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thromboembolism

Brief summary

Patients hospitalized in internal wards are at risk for VTE. The current guidelines recommend the use of thromboprophylaxis for 7-10 days among patients who are at increased risk for VTE. Yet several retrospective studies have shown that the compliance with this guideline is low. Physicians are often reluctant to administer LMWH to their fragile patients mainly because they are not convince that the risk associated with such therapy is greater than the risk for VTE. In the current study, data concerning the use of thromboprophylaxis among patients admitted to the medical wards will be collected. The occurrence of bleeding or thrombotic event will be evaluated prospectively.

Detailed description

Data concerning the use of LMWH among patients admitted to the medical wards at the Hadassah University Hospital will be collected prospectively from the electronic medical records. The occurrence of bleeding episodes or thrombotic events will be followed for the next 90 days following discharge from the hospital. The percent of patients actually treated by LMWH among patients entitled for such therapy according to the most updated international guidelines will be evaluated. The risk of minor and major bleeding will be compared among those given thromboprophylaxis and those who were not treated. Similar comparison will be made for thrombotic events.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients admitted to the medical wards at the Hadassah University Hospital

Exclusion criteria

* None

Design outcomes

Primary

Measure	Time frame	Description
Thrombosis	90 days	Rate of thrombotic events within 90 days following discharge
Bleeding	90 days	Rate of minor and major bleeding episodes within 90 days following discharge
Compliance	90 days	Rate of compliance with ACCP guidelines concerning thromboprophylaxis of non-surgical patients.

Outcome results