Role of SWE-change After TIPS in the Prediction of Prognosis After TIPS

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03072615

Acronym

TIPS-SWE

Enrollment

Registered

2017-03-07

Start date

2013-04-01

Completion date

2016-02-29

Last updated

2017-03-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Cirrhoses, Portal Hypertension

Brief summary

The aim of our prospective multicenter study was to investigate the prognostic value of the acute and long-term changes of liver stiffness in patients receiving a transjugular intrahepatic portosystemic shunt (TIPS).

Detailed description

We included 83 patients receiving TIPS for prevention of rebleeding, therapy-refractory ascites or both. Hemodynamic parameters were assessed before TIPS and after TIPS insertion. 16 patients from Freiburg underwent TE immediately before and after TIPS. In 67 patients from Bonn, SWE of liver and spleen, as well as clinical and biochemical parameters were assessed before TIPS, seven days and six weeks after TIPS.

Interventions

DIAGNOSTIC_TESTStiffness measurement

Transient Elastopgraphy (TE) or Shear-Wave-Elastography

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* TIPS insertion and had reliable SWE or TE measurement

Exclusion criteria

* contraindication for TIPS * no reliable SWE or TE measurement

Design outcomes

Primary

Measure	Time frame
Survival	3 months

Secondary

Measure	Time frame
Acute-on-chronic Lvier failure	3 months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 26, 2026