New, Previously Unknown, Uses of Optical Coherence Tomography Angiography (OCTA)

New, Previously Unknown, Uses of Optical Coherence Tomography Angiography (OCTA): Sickle Cell Maculopathy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03068702

Acronym

OCTA

Enrollment

Registered

2017-03-03

Start date

2016-08-21

Completion date

2017-02-21

Last updated

2017-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sickle Cell Retinopathy

Brief summary

Sickle cell maculopathy was sparingly mentioned in the literature before despite the fact that sickle cell disease or sickle cell trait is common in people of many areas of the world. This study shows that OCTA is a very valuable, non invasive, office procedure that may well be used in diagnosing this disease.

Detailed description

this is a clinical study of two African Canadian patients that were diagnosed with sickle cell trait. I used OCTA to show macular vascular occlusions that usually happen with this disease.

Interventions

DEVICEOptical Coherence Tomography Angiography

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

people with sickle cell trait or sickle cell disease -

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
vascular changes seen in the macular vasculature of people with sickle cell disease/ trait as compared to macular vasculature of normal macula.	through study completion, an average of one year	in this angiography the delicate vasculature of the macula can be clearly visualized and documented.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026