Coronary Bifurcation Lesion
Conditions
Keywords
Coronary Bifurcation Lesion, 2nd generation drug-eluting stent
Brief summary
The COBIS III registry is a multi-center, real-world registry of 2nd generation drug-eluting stenting in coronary bifurcation lesions in South Korea. From 21 major coronary intervention centers in Korea, a total of 3,000 patients (anticipated) will be enrolled in this database between January 2010 and December 2014. The aim of the study was to investigate long-term clinical results and predictors of adverse outcomes after percutaneous coronary intervention with 2nd generation drug-eluting stents for coronary bifurcation lesions in South Korea.
Interventions
None listed
Sponsors
Samsung Medical Center
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age \>=19 years * Any type of de novo bifurcation lesion in major epicardial artery: unprotected left main coronary bifurcation lesion, LAD - diagonal, LCX-OM, distal RCA bifurcation. (Excluding RCA-RV branch bifurcation, branch bifurcation) * Side branch or LCX reference diameter \>= 2.3 mm and at least stentable with 2.5 mm stent * Treated with drug-eluting stent during the period of 2010. 1 \ 2014. 12
Exclusion criteria
* Protected left main disease previous CABG for LAD or LCX territory * Cardiogenic Shock * History of CPR in the same hospitalization * Patients with severe left ventricular systolic dysfunction (ejection fraction \< 30%)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Target lesion failure | 5 years | composite of cardiac death, myocardial infarction, or target lesion revascularization |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Cardiac death | 5 years | All deaths were considered cardiac cause unless obvious non-cardiac causes could be identified |
| Myocardial infarction | 5 years | an elevation of creatine kinase-myocardial band or troponin level greater than the upper limit of normal with concomitant ischemic symptoms or electrocardiography findings indicative of ischemia |
| Target lesion revascularization | 3 years | repeat PCI of the lesion within 5 mm of the inserted stent |
| Stent thrombosis | 5 years | the Academic Research Consortium as definite, probable, or possible |
Countries
South Korea
Outcome results
None listed