Lichen Amyloidosis
Conditions
Keywords
Methylene blue, photodynamic therapy, primary cutaneous localized amyloidosis, lichen amyloidosis
Brief summary
Efficacy of Methylene blue mediated Photodynamic therapy for primary localized cutaneous amyloidosis treatment in Asians, pilot study.
Interventions
The 2% MB aqueous solution was applied to the lesion until saturation occurred, followed by a occlusive dressing and rest period of 30 minutes. After the rest period, the lesion was immediately illuminated with incoherent red light (peak emission spectrum at 630-640 nm)
Sponsors
Chulalongkorn University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients, aged \> 18 years old with lichen amyloidosis diagnosed by using clinical presentation and pathological findings.
Exclusion criteria
* Those with systemic disease associated cutaneous amyloidosis * Pregnancy or lactating woman * Those who are allergic to urea, olive oil * Those who are photosensitive to ultraviolet radiation * Those who had been previously treated with any of which -medications, radiation, laser within 3 months and 1 month for topical therapy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Roughness evaluation by using visioscan | Change from baseline roughness at every 2 weeks up to 16 weeks | The improvement of roughness during the treatment |
Countries
Thailand
Contacts
PRINCIPAL_INVESTIGATOREinapak Amnarttrakul, M.D.
Chulalongkorn University
Outcome results
None listed