Obesity, Overweight, Life Style
Conditions
Keywords
Caloric Restriction, Diet, Obesity, Overweight, Sedentary Lifestyle, Weight loss, Women
Brief summary
Negative-calorie diet is among the popular dieting guides for weight loss; however, there is still little knowledge about this method. The present study aimed to determine the effects of negative-calorie diet on weight loss and lipid profile, and to compare its efficiency with low-calorie diet.
Sponsors
P.L.Shupik National Medical Academy of Post-Graduate Education
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
45 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* Non-smokers and weight-stable (± 2 kg, for more than one year) with no history of regular exercise in at least three months before the study.
Exclusion criteria
* History of CVD and other disorders such as diabetes, depression, eating disorders, chronic medications, kidney disease, cancer, food allergies or intolerances to items used in meals. * Subjects with abnormality in thyroid or Electrocardiograph, any history of anti-obesity medication or weight loss drugs or dietary supplementations for weight control.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Triglycerides (TG) | pre-study | assessed in mg/dl |
| Weight | pre-study | assessed in kg |
| Total cholesterol (Total-C) | pre-study | assessed in mg/dl |
| High-density lipoprotein -cholesterol (HDL-C) | pre-study | assessed in mg/dl |
| Low-density lipoprotein -cholesterol (LDL-C) | pre-study | assessed in mg/dl |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Weight | 3-month | assessed in kg |
| Total cholesterol (Total-C) | 3-month | assessed in mg/dl |
| High-density lipoprotein -cholesterol (HDL-C) | 3-month | assessed in mg/dl |
| Low-density lipoprotein -cholesterol (LDL-C) | 3-month | assessed in mg/dl |
Outcome results
None listed