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The Effect of a Protein Hydrolysate on Muscle Strength Recovery

The Effect of a Protein Hydrolysate on Muscle Strength Recovery in Athletes

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03063346
Enrollment
48
Registered
2017-02-24
Start date
2016-06-06
Completion date
2017-02-20
Last updated
2017-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle Strength Recovery

Brief summary

Overtraining is a real problem for (semi-)professional athletes. Overtraining is often caused by the bodies' lack of ability to recover between training. In addition, during high intensity training reactive oxygen species are formed up to 20 fold compared to resting values. This causes increased muscle tissue damage after intense exercise, which slows down recovery. Improving recovery may increase an athlete's ability to reach higher training volumes resulting in establishing a higher performance plateau. It is known that hydrolyzed proteins have a positive effect on muscle protein synthesis due to its faster absorption rate. Therefore, it is hypothesized that a known protein hydrolysate may have positive effects on strength recovery.

Interventions

DIETARY_SUPPLEMENTProtein hydrolysate high dose
DIETARY_SUPPLEMENTProtein hydrolysate low dose
DIETARY_SUPPLEMENTPlacebo

Sponsors

BioActor
Lead SponsorINDUSTRY

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy individuals (based on their medical history provided during a general health questionnaire) * Participants are amateur or (semi-) professional athletes in resistance or interval sports (engage in \>6 hours of intense physical activity per week). * Age 18 - 35 * Experience in resistance training

Exclusion criteria

* Use of creatine supplements and/or anabolic steroids. * Allergy to test product/protein * Allergy to specific protein hydrolysate * BMI lower than 18 or higher than 30. * Lack of technique in correctly performing a barbell squat (judged by sports physiologist). * Recent muscle injury in legs or back less than one month before the start of the study. * Cardiovascular complications * Use of medication * Administration of investigational drugs or participation in any scientific intervention study which may interfere with this study (to be decided by the principle investigator), in the 180 days prior to the study. * Abuse of products; alcohol (\> 20 alcoholic units per week) and drugs

Design outcomes

Primary

MeasureTime frameDescription
Muscle strength recovery4 weeksdifference in peak force between the exhaustion challenge and the recovery challenge, measured with a linear encoder during a squat exercise

Secondary

MeasureTime frameDescription
Blood lactate buildup4 weeksin mmol/L, measured trough a finger prick after exhaustion and recovery challenge
Body composition4 weeksfat percentage, based on 4-point skin fold measurement
Exercise volume4 weeksamount of repetitions x time taken x power, measured with a linear encoder during squat exercise
Peak force output4 weeksmeasured with a linear encoder during the squat exercise

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026