Chest Compression and Cerebral Oxygenation During Cardiopulmonary Resuscitation

Can Sufficient Cerebral Oxygenation be Provided in a Synchronized Manner With Chest Compression During Cardiopulmonary Resuscitation?

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03062306

Acronym

CPR

Enrollment

Registered

2017-02-23

Start date

2017-05-31

Completion date

2018-08-31

Last updated

2019-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Providing Sufficient Cerebral Oxygenation During CPR

Keywords

Cerebral Oxygenation, Cardiopulmonary Resuscitation, Chest Compression

Brief summary

In recent years, monitorizations during Cardiopulmonary Resuscitation (CPR) are inadequate to show the sufficiency of cerebral oxygenation. During CPR, insufficient chest compressions have critical importance for neurological results and life quality after the return of spontaneous circulation (ROSC).

Detailed description

The Near-Infrared Spectroscopy (NIRS), which is used in measuring the cerebral tissue oxygenation is one of the latest technologies that allow the measurement of brain oxygen saturation. With this study, the issue of whether sufficient cerebral oxygenation is provided during CPR applied to patients that have Cardiac Arrest (CA) will be investigated, and the effect of CPR on the patient prognosis after ROSC will be examined. In this study, the aim is to investigate whether sufficient oxygenation is provided in synchronization with chest compressions during CPR; and to test the regional brain tissue saturation with rSO2 measurement, and the prognosis with Full Outline of UnResponsiveness (FOUR) Score in patients with ROSC.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1\. All patients undergoing cardiac arrest in intensive care unit

Exclusion criteria

1. Head injury and intracranial bleeding 2. Cerebral ischemic vascular event 3. Pulmonary diseases that may affect blood-oxygen levels 4. Below the age of 18

Design outcomes

Primary

Measure	Time frame	Description
The levels of regional brain tissue oxygen saturation (rSO2) providing with chest compressions during Cardiopulmonary Resuscitation (CPR)	About six month	The data will be obtained by using the Near Infrared Spectroscopy (NIRS) Device and will be recorded rSO2 measurement during the resuscitation of the Cardiac Arrest (CA) patients

Secondary

Measure	Time frame	Description
Change from baseline in consciousness on Full Outline of UnResponsiveness (FOUR) Score at one week	For a week after ROSC	The patient's consciousness will be evaluated by FOUR score in patients with ROSC

Countries

Turkey (Türkiye)

Outcome results