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Efficacy of a Culturally Adapted Cognitive Behavioural Internet-delivered Treatment for Depression

Assessing the Efficacy of a Culturally Adapted Cognitive Behavioural Internet-delivered Treatment for Depression: Protocol for a Randomised Controlled Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03062215
Acronym
CAiCBT
Enrollment
127
Registered
2017-02-23
Start date
2016-08-02
Completion date
2018-06-01
Last updated
2018-09-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Keywords

Culturally adapted psychotherapy, Internet-delivered treatment, Depression, Latin America

Brief summary

The study seeks to evaluate the efficacy of a culturally adapted internet-delivered treatment for depression in Colombia. The research involves two studies: (a) the cultural adaptation of the Space from Depression cognitive-behavioural internet-delivered programme, and (b) the implementation of the culturally adapted intervention using a randomised controlled trial methodology. The study will be a first contribution of a culturally adapted low-intensity internet-delivered intervention with Latin Americans.

Detailed description

Depression is the principal cause of disability in the world. High rates of prevalence of depression in general populations and college students have been found worldwide and in various cultural groups. For instance, a 12-month prevalence rate has been estimated in the U.S. at 9.5% and in Europe at 8.5% of the population. In Colombia, 12-month prevalence is between 6.2% and 12.1%. The Colombian National Mental Health Survey has estimated point prevalence of mild to moderate depressive symptoms at 15.6% and severe depressive symptoms at 4.2% of adults. On the other hand, there are significant barriers for accessing mental health services in Colombia. About 50% of the population does not have access to health services, while the majority of the population with mental health problems do not have adequate mental health insurance coverage. Although low-intensity interventions for depression have been developed in western high-income countries and these interventions therefore have been influenced by their specific cultural context (for example, Ireland, UK, Australia), it is important to consider how cultural context may impact on the adaptation for use in LMICs such as Colombia. The authors argue that cultural aspects need to be taken into consideration when translating and adapting interventions to help guarantee similar results to what have been achieved in high-income countries. General method Aims and Hypothesis: We aim to assess the efficacy of a culturally adapted cognitive behavioural internet-delivered treatment for college students with depressive symptoms in Colombia. In line with other studies in high-income countries (HICs), and using an already established intervention, we hypothesise that the culturally adapted Space from Depression programme will be efficacious, with significant changes within the treatment group and differences post-treatment between the active treatment and the waiting list control group. The study is a mixed method approach utilising in study 1, quantitative and qualitative methods to assist in the cultural adaptation of the Space from Depression intervention and in study 2 a randomised control design to examine the efficacy of the culturally-adapted intervention. Procedure The programme Space from Depression will be culturally adapted for a Colombian population using cultural sensitivity and ecological validity frameworks, including principles from cross-cultural assessment research. (Study 1). Once the programme is culturally adapted, it will be tested using a randomised controlled trial methodology (Study 2).

Interventions

Space from Depression programme (Yo puedo sentirme Bien -Spanish version) consists of seven modules of cognitive-behavioural therapy. The treatment includes self-monitoring, behavioural activation, cognitive restructuring, and challenging core beliefs. All modules have the same structure and format, which consist of quizzes, videos, educational content, activities with homework suggestions and a module review page.

Sponsors

Irish Research Council
CollaboratorOTHER
Silver Cloud Health
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No

Inclusion criteria

* 18 years old and above * Mild to moderately severe depressive symptoms: (PHQ-9 score 10-19)

Exclusion criteria

* Severe depressive symptoms \>19 on PHQ-9 * Suicidal ideation or intent: Score of 2 or above on PHQ-9 question 9 * Psychosis * Currently in psychological treatment for depression * On medication for less than 1 month * Alcohol or drugs misuse * Previous diagnosis of an organic mental health disorder * Depression preceding or coinciding a diagnosed medical condition

Design outcomes

Primary

MeasureTime frameDescription
Patient Health Questionnaire -96 monthsdepression symptoms

Secondary

MeasureTime frameDescription
Generalised Anxiety Disorder 76 monthsanxiety symptoms

Other

MeasureTime frameDescription
Satisfaction with Treatment Questionnaire2 monthsPatient satisfaction
Helpful Aspects of Therapy Questionnaireweekly for 7 weeksSignificant events

Countries

Colombia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 7, 2026