75 Years Old and More, Female Breast Cancer, Surgery
Conditions
Keywords
Breastcancer, Standardized Geriatric Evaluation, Onco-Geriatric Filter
Brief summary
The risk of diagnosis of cancer increases with age, especially breast cancer in elderly women. Elderly population is heterogeneous, regarding physiological reserves, comorbidities, disability and geriatric conditions. Comprehensive geriatric assessment (CGA) is a multidimensional approach to determine geriatric profile, in helping the therapeutic strategy. In-patients with diagnosis of cancer are screened with the FOG (oncology geriatric filter), to identify vulnerable subjects who may benefit from CGA. This scale of ten questions includes geriatric domains such as functional status, nutrition, mood, cognitive abilities and comorbidities. In elderly patients with breast cancer considered as fit (FOG=0), CGA is not necessary before adjuvant treatment. In vulnerable patients (FOG ≤ 1 and \< 3), CGA is held in routine to discuss the adjuvant therapy feasibility. Patients with FOG ≥ 4 underwent CGA if palliative care is considered. Patients in the intermediate group (FOG 1-3) are randomized to determine time of CGA, before or after surgery. The aims of this study are to assess the outcomes regarding the time of CGA, in elderly female patients with breast cancer management, and to define the optimal place of CGA in care pathway.
Interventions
BEHAVIORALMedical consultation for a Standardized Geriatric Evaluation
Sponsors
Poitiers University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
75 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* First breast cancer localized, indication of surgery * Onco-geriatric filter (FOG) \>= 1 ou \< 4
Exclusion criteria
* Male, less of 75 years old * Contraindication of surgery * Breast cancer with metastasis * Onco-geriatric filter (FOG) = 0 or 4
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare Comprehensive Geriatric Assessment before the surgery and Comprehensive Geriatric Assessment after the surgery | 5 years |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Quality of life of patients | 5 years | Questionnary EORTC QLQ - BR33 |
| Patient satisfaction with their management | 5 years | Questionnary REPERES 60 - Consumer Satisfaction Survey |
| Compare proportions of patients who received adjuvant chemotherapy and / or radiation standard | 5 years | — |
| Compare time to take care of Comprehensive Geriatric Assessment before the surgery and Comprehensive Geriatric Assessment after the surgery | 5 years | — |
| Compare the proportions of patients receiving adjuvant therapy, including complete hormone therapy | 5 years | — |
Countries
France
Outcome results
None listed