Heart Failure
Conditions
Keywords
Potassium, Nutrition
Brief summary
This study evaluates the safety and physiologic effects of increasing dietary potassium intake in individuals with heart failure.
Interventions
OTHERHigh potassium diet
An increase in consumption of high potassium fruits and vegetables
Sponsors
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Masking description
Treating physicians and participants were not blinded to randomization. Investigators performing randomization and analysis of dietary intake were blinded.
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* All patients classified as having HF, both systolic and diastolic. * New York Heart Association class II-III symptoms. * Treatment with an beta blocker, ACE inhibitor, or angiotensin receptor blocker without any adjustment over the previous month * Intake at baseline of ≤ 3 servings of fruits and vegetables per day. Servings defined by Health Canada's food guide.
Exclusion criteria
* Patients with an episode of decompensated heart failure, acute coronary syndrome, or revascularization within the previous 3 months of study inclusion. * Patients receiving insulin therapy * Glomerular filtration rate \< 40mL/min/1.73 m2 * Pregnancy and lactation (women of childbearing potential will be included but will have to have a negative pregnancy test prior to inclusion). * Inability to provide informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum potassium concentration | 10 days and 3 weeks |
Outcome results
None listed