Study to Investigate TIVA With Propofol on Postoperative Pain and Side Effects

Retrospective Study to Investigate Total Intravenous Anaesthesia (TIVA) With Propofol on Postoperative Pain and Side Effects After Surgery

Status

Withdrawn

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03058354

Enrollment

Registered

2017-02-20

Start date

2017-01-01

Completion date

2020-12-31

Last updated

2022-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain

Brief summary

Propofol is a commonly used anaesthetic with rapid recovery and less side effects and total intravenous anaesthesia (TIVA) with propofol is a common technique now. The reduction on certain serum pro- inflammatory cytokines may lead to more smooth post- surgical recovery. Recent case report proved the analgesic effect of propofol infusion. However other animal and clinical studies showed controversial result. The aim of this retrospective study is to investigate the postoperative analgesic effects and side effects of intraoperative TIVA with propofol in patient undergoing surgery at Queen Mary Hospital, Hong Kong between 2014 to 2016.

Detailed description

Objectives: 1. To investigate the analgesic effects of propofol. 2. To evaluate the effect of propofol on postoperative adverse events. Methods: Retrospective audit. Data Collection: 1. Demographic data; 2. Types of analgesic techniques; 3. Type of pain relief modalities; 4. Pain score up to 72 hours postoperatively; 5. Postoperative opioid consumption; 6. Incidence of adverse events during APS care; 7. Patients' satisfaction on pain relief.

Interventions

DRUGPropofol

Patient undergoing surgery at Queen Mary Hospital, Hong Kong between 2014 to 2016 using intraoperative TIVA with propofol.

PROCEDUREgeneral anaesthesia

Patient undergoing surgery at Queen Mary Hospital, Hong Kong between 2014 to 2016 using general anaesthesia methods other than intraoperative TIVA with propofol.

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Anaesthetic records and acute pain service records of patient undergone surgery between 2014 to 2016 in Queen Mary Hospital would be retrieved from the computer.

Exclusion criteria

* Essential data were missing. * Patient participating in other research projects. * Changes in postoperative pain management technique. * Patients could not be assessed post-operatively for pain (i.e. post-operative IPPV)

Design outcomes

Primary

Measure	Time frame	Description
pain score	up to postoperative day 3	pain score using numeral rating scale

Secondary

Measure	Time frame	Description
analgesic consumption	up to postoperative day 3	analgesic consumption base on patient drug record

Countries

Hong Kong

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026