Comparison of Apnea Tolerance in Two Positions of Patients With BMI 30-40

Comparison of Apnea Tolerance in Two Positions of Patients With Body Mass Index (BMI) 30-40

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03056820

Enrollment

Registered

2017-02-17

Start date

2010-05-31

Completion date

2011-03-31

Last updated

2017-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General Surgery

Keywords

tracheal intubation

Brief summary

The purpose of this study is to compare the effect of the 25° head-up position versus the 55° head-up position on tolerable apnea time (TAT) after induction of general anesthesia in patients with a body mass index (BMI) of 30-40.

Interventions

OTHER25° head-up position

Participant will be positioned at 25° angle for procedure.

OTHER55° head-up position

Participant will be positioned at 55° angle for procedure.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

HEALTH_SERVICES_RESEARCH

Masking

SINGLE (Outcomes Assessor)

Masking description

The person measuring and recording the study data will be blinded.

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* American Society of Anesthesiologists (ASA) physical status I-III * Body Mass Index (BMI) of 30-40 * Scheduled for an elective surgery that requires tracheal intubation

Exclusion criteria

* Patients with abnormalities of the upper airway that require awake tracheal intubation * Asthma * Chronic obstructive pulmonary disease * Congestive heart failure * Pregnant patients

Design outcomes

Primary

Measure	Time frame	Description
Tolerable Apnea Time (TAT)	Time between start of induction of general anesthesia (SpO2 100%) to decline of SpO2 94%, up to eight minutes	Measure of the TAT between groups to determine if the TAT is a function of the participant's position.

Secondary

Measure	Time frame	Description
Length of time to intubation (TTI)	Time between start of the tracheal intubation procedure to completion of tracheal intubation, up to 2 minutes	—
Peripheral arterial hemoglobin oxygen saturation (SpO2) trough	Time until SpO2 decreased to 92%, up to 8 minutes	Measure of the rebound SpO2. It is the lowest SpO2 reading reached subsequent to start of mechanical ventilation at the SpO2 value of 94% and it represents final completion of SpO2 decline.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026