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Prevalence of Bacteria Following Endodontic Treatment

Prevalence and Phenotype of Oral Enterococcus Faecalis

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03055975
Enrollment
200
Registered
2017-02-16
Start date
2013-01-30
Completion date
2018-10-30
Last updated
2017-02-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Root Canal Infection

Keywords

Bacteria, Root canal treatment, Endodontics

Brief summary

Sampling of accessed root canals with endodontic paper points during treatment and immediately pre-obturation of endodontic root canals was carried out.

Detailed description

Following ethical approval (REC ref: 05/Q0705/051), informed consent was obtained from patients undergoing root canal treatment.The teeth included in the study had been referred to a specialist centre for the treatment of endodontic infection. They all responded negatively to vitality tests and presented pre-operative apical radiolucencies. The source population were referred by their general dental practitioner into specialist endodontic clinics of Guy's Hospital, King's College London Dental Institute.Treatments on the teeth were carried out by a total of 19 postgraduate endodontic students.

Interventions

DIAGNOSTIC_TESTDetection of residual vital bacteria in the root canal space

Detection of residual vital bacteria in the root canal space. No intervention, as it is an observational study. Vital bacteria are looked for in the samples taken from the root canal space.

Sponsors

Guy's and St Thomas' NHS Foundation Trust
CollaboratorOTHER
King's College London
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Patients with single or multi-rooted teeth undergoing root canal treatment.

Exclusion criteria

* For certain aspects of the study secondary treatments and vital teeth are excluded.

Design outcomes

Primary

MeasureTime frameDescription
Detection of residual bacteria during and post root canal treatmentJune 2016Using a vital fluorescent stain bacteria sampled from the root canal space were detected during and post root canal treatment.

Countries

United Kingdom

Contacts

Primary ContactFederico Foschi, Dr
federico.foschi@kcl.ac.uk+44 (0)020 7188 7188
Backup ContactDylan Herzog, Mr
dylan.b.herzog@kcl.ac.uk+44 (0)207 188 1789

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 27, 2026