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Oxygenation of Paravertebral Muscles During Exercise in Chronic Low Back Pain Patients

Oxygenation of Paravertebral Muscles During Exercise in Chronic Low Back Pain Patients

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03055182
Acronym
OXYLOM
Enrollment
33
Registered
2017-02-16
Start date
2017-01-11
Completion date
2024-12-10
Last updated
2025-12-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low Back Pain, Muscular Weakness, Rehabilitation Program

Keywords

Isokinetic, oxygenation, deoxygenation, aerobic metabolism

Brief summary

The study evaluate paraspinal aerobic metabolism of chronic low back pain patients and healthy people during an original and standardized isokinetic protocol. The aim of this study is to determine a potential alteration of muscular aerobic metabolism in low back pain patients, in order to establish the underlying cause of pain and muscular fatigability characterizing low back pain patients. Then, the aim is to determine if functional rehabilitation program can improve it. the unit of care have access to metabolic adaptations in measuring the muscular oxygenation and the pulmonary oxygen consumption, using near infrared spectroscopy and gas analyser.

Interventions

Patients participate during 4 weeks to a physical rehabilitation program.

Sponsors

University Hospital, Lille
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* For Low back pain patients: suffering from low back pain for at least 3 month * For control subject: no back pain in the past year

Exclusion criteria

* Chronic cardiovascular, pulmonary, metabolic, neurologic disease

Design outcomes

Primary

MeasureTime frameDescription
Deoxyhemoglobin20 minutesExpressed in arbitrary unit, at rest and during the isokinetic exercises (2 exercises of 5 minutes)

Secondary

MeasureTime frameDescription
Work rate10 minutesTotal work measured by the dynamometer in Joules during each exercises
Rate of perceived exertion10 minutesBases on the Borg's Scale, evaluating the perceived exertion on a scale from 6 to 20
Oxygen consumption20 minutesMeasured in mL/min/kg, at rest and during the isokinetic exercises (2 exercises of 5 minutes)
Muscular blood volume20 minutesExpressed in arbitrary unit, at rest and during the isokinetic exercises (2 exercises of 5 minutes)
Sorensen test20 minutestest is a timed measure used to assess the endurance of the trunk extensor muscles. It is used to assist in the prediction of the incidence and occurrence of low back pain in patients.
Pain10 minutesBases on a visual analogic scale evaluating the pain on a scale from 0 to 10

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026