Skip to content

Perioperative Lung Function Monitoring After Anatomic Lung Resections

Perioperative Lung Function Monitoring After Anatomic Lung Resections

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03054675
Acronym
PLF
Enrollment
328
Registered
2017-02-15
Start date
2013-06-01
Completion date
2016-06-30
Last updated
2017-02-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Diseases, Lung Function Decreased, Surgery

Keywords

lung resection, lung function, VATS, Thoracotomy

Brief summary

Aim of this study was to prospectively investigate the correlation between postoperative spirometry values and pulmonary complications after anatomic lung resections. In addition, the investigators compared postoperative pulmonary function changes between open and minimally invasive approaches.

Detailed description

All patients undergoing an anatomical lung resection at the investigators' institution were evaluated for this study. Underage patients and those undergoing extended resections (including resection of the chest wall and/or diaphragm) and/or bronchoplastic procedures were excluded. In every eligible patient undergoing an anatomic lung resection, preoperative spirometry was performed using a handheld spirometer on the day before surgery and on every second day after surgery was performed until patient discharge. The absolute values of FEV1 were recorded by an independent study nurse and noted on a separate sheet not available to the treating doctors. At the end of the study period FEV1 values were evaluated especially with focus on their correlation with postoperative pulmonary complications (i.e. pneumonia, acute exacerbation of COPD, air leak and atelectasis). Furthermore lung function values of patients undergoing 'open' resections were compared with patients undergoing minimally invasive resections.

Interventions

DIAGNOSTIC_TESTSpirometry

Absolute FEV1 is measured in every patient using a handheld spirometer

Sponsors

Insel Gruppe AG, University Hospital Bern
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients undergoing anatomical lung resection * Written informed consent

Exclusion criteria

* Underage patients * Extended resections including resection of chest wall or diaphragm * Bronchoplastic resections

Design outcomes

Primary

MeasureTime frameDescription
Decrease in FEV1up to 6 days after surgeryPostoperative loss of FEV1 in percent of absolute preoperative levels

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026