Airway Obstruction
Conditions
Brief summary
In a prospective, observational study the investigators compared resistance values measured using the airway perturbation device (APD) to impulse oscillometry and spirometry. The investigators also created reference equations for normal APD resistance ranges using the data from clinically normal volunteers.
Interventions
DIAGNOSTIC_TESTAirflow pertubation device
Participants have airway resistance measured at the mouth by tidal breathing into a mouth-piece connected to the airflow perturbation device.
Sponsors
Walter Reed National Military Medical Center
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Male and female subjects \> 18 years * Referred for PFTs and/or PSG at WRNMMC * All races and ethnicities will be included * Pregnant women will be included
Exclusion criteria
* \< 18 years of age * If mental status is questionable, the patient will be excluded at the discretion of the consenting provider * Unable/unwilling to follow the directions necessary for APD use
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants with APD correlation > 0.5 with spirometry | At enrollment | Respiratory resistance ( cm H20/L/s) measured with APD correlated with volumes (in liters) measured by spirometry. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants with APD correlation > 0.5 with impulse oscillometry | At enrollment | Respiratory resistance (cm H20/L/s) measured with APD correlated with resistance (cm H20/L/s) measured using impulse oscillometry |
Outcome results
None listed