Placental Membrane for Root Coverage

Treatment of Gingival Recession Using a Coronally Advanced Flap Procedure With or Without Placental Membrane

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03053921

Enrollment

Registered

2017-02-15

Start date

2015-08-19

Completion date

2016-06-15

Last updated

2017-02-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival Recession

Keywords

gingival recession, Zuchellis technique,, placental membrane

Brief summary

Aim of the study was to evaluate the clinical efficacy of placental membrane with coronally advanced flap in covering single and multiple Miller's class I and II gingival recession defects.

Detailed description

STUDY DESIGN A total number of 60 teeth in 15 subjects were selected. Patients with bilateral Miller's class I and II gingival recession defects in the maxillary or mandibular anterior and premolar region were selected and divided into two groups using a split mouth design. GroupI (Control) -30 recession defects treated with coronally advanced flap alone, using Zucchelli's technique. Group II (Test) - 30 recession defects treated with coronally advanced flap, using Zucchelli's technique along with placental membrane. . CLINICAL PARAMETERS: 1. Probing Pocket Depth(PPD) 2. Clinical Attachment Level(CAL) 3. Height of Gingival Recession(HGR) 4. Width of Gingival Recession(WGR) 5. Width of Keratinized Gingiva(WKG) The clinical parameters were assessed & recorded on 0 day, 90th day and 180th day

Interventions

PROCEDURErecession coverage

recession coverage done using Zuchellis technique

PROCEDURErecession coverage and membrane

recession coverage done using Zuchellis technique with placental membrane

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

23 Years to 55 Years

Healthy volunteers

Yes

Inclusion criteria

1. Patients within the age group 23 to 55 years 2. Bilateral, upper or lower, Miller's class I and Class II gingival recession defects confined to the anterior and premolar region. 3. Presence of identifiable cemento-enamel junction 4. Presence of keratinized tissue apical to the exposed root

Exclusion criteria

1. Systemic complications 2. Occlusal interferences 3. Any contraindication for periodontal surgery and taking medication which are known to interfere with periodontal tissue health or healing 4. Previous periodontal surgery on the involved site 5. Smokers 6. Pregnant and lactating mothers

Design outcomes

Primary

Measure	Time frame	Description
Height of Gingival recession	6 months	The height of gingival recession was measured from the cemento-enamel junction to the gingival margin using Williams periodontal probe

Secondary

Measure	Time frame	Description
Clinical attachment level	Baseline and 6 months	Clinical attachment level is measured as the distance between a fixed point on the crown such as cementoenamel junction to the base of the pocket using williams periodontal probe
Width of Keratinized Gingiva	Baseline and 6 months	It is measured as the distance from the gingival margin to the mucogingival junction using williams periodontal probe

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026