Low Level Laser Therapy for Hyposalivation

Different Low Level Laser Protocols for Therapy of Hyposalivation

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03049943

Enrollment

Registered

2017-02-10

Start date

2014-05-05

Completion date

2014-09-16

Last updated

2017-02-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyposalivation

Keywords

low level laser therapy, hyposalivation

Brief summary

The aim of this study was to compare the effects of different wave lengths of LLLT on salivation in participants suffering from hyposalivation. This study included 30 participants whose major salivary glands were treated with low intensity diode laser BTL2000 (Medical Technologies, s.r.o., Czech Republic) during 10 consecutive days. Patients were randomly assigned in two groups, each of 15 patients, and treated with LLLT of 830 nm and LLLT of 685 nm, respectively. The whole unstimulated and stimulated saliva was measured each day during 10 days, before and after laser treatment and 10th day after treatment was ended.

Detailed description

Low level laser treatment has proved to be effective for a wide range of oral pathologies including oral dryness, but the literature still lacks reports of clinical trials and protocols. The aim of this study was to evaluate the effects of two different laser wave lengths on salivation of patients suffering from hyposalivation. This with purpose to possibly find the optimum laser wavelength for the treatment, and to determine the better protocol for the patients suffering from hyposalivation. This study included 30 patients whose major salivary glands were treated with low intensity diode laser BTL2000 (Medical Technologies, s.r.o., Czech Republic) during 10 consecutive days. Patients were randomly assigned in two groups, each of 15 patients, and treated with LLLT of 830 nm and LLLT of 685 nm, respectively. The whole unstimulated and stimulated saliva was measured in graduated tubes each day during 10 days, before and after laser treatment and 10th day after treatment was ended.

Interventions

DEVICElow level laser

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

FEMALE

Age

52 Years to 85 Years

Healthy volunteers

Yes

Inclusion criteria

* patients suffering from hyposalivation, with medical histories free of radiotherapy and Sjögren's syndrome

Exclusion criteria

* medical histories of radiotherapy and Sjögren's syndrome

Design outcomes

Primary

Measure	Time frame	Description
Difference in average salivary flow rate, before and after low level laser treatment	10 days	The whole unstimulated and stimulated saliva was measured each day during 10 days, before and after laser treatment

Secondary

Measure	Time frame	Description
Average salivary flow rate	1 day (Average salivary flow rate 10th day after the end of LLLT)	Average salivary flow rate 10th day after the end of LLLT

Countries

Croatia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026