Study of Arterial Recanalization of the Central Retinal Artery Occlusions

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03049514

Acronym

RECANAL

Enrollment

Registered

2017-02-10

Start date

2016-12-23

Completion date

2022-04-02

Last updated

2022-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Central Retinal Artery Occlusion

Keywords

Thrombolysis, Recanalization, Dynamic retinal angiography

Brief summary

Central retinal artery occlusions (CRAO) are the equivalent of an ischemic stroke (IS) at the retinal level. They share the same risk factors and common pathology. Their incidence is lower (8.5 / 100,000) and the functional prognosis is unfavorable in 80% of cases with visual acuity (VA) \<1/10. The diagnosis of an CRAO is clinically based on the sudden occurrence of a decrease in deep visual acuity with fundamentally signs of reactive ischemia. There is no data on early retinal arterial recanalization after CRAO, nor on the relationship between early recanalization (spontaneous or post-thrombolysis) and visual prognosis.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Central Retinal Artery Occlusion ≤ 24 hours

Exclusion criteria

* Retinal Dynamic angiography not performed within 48 hours of onset of symptoms * Occlusion of a branch of the central retinal artery

Design outcomes

Primary

Measure	Time frame	Description
Dynamic retinal angiography data at 24 hours (+/- 24 hours)	24 hours (+/- 24 hours) following the beginning of symptoms	Proportion of patients with early arterial recanalization.The recanalization rate will be compared between thrombolysed patients and non-thrombolysed patients

Countries

France

Outcome results