Enteral Feeding Intolerance
Conditions
Brief summary
A retrospective chart review to assess feeding tolerance in adults who had been switched from an intact protein formula to a peptide-based formula due to feeding intolerance in a complex continuing care facility.
Interventions
OTHEREnteral Formula
Enteral feeding with a peptide-based formula.
Sponsors
Société des Produits Nestlé (SPN)
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* \> 18 years of age on admission to facility * Prescribed enteral nutrition with the goal to provide at least 90% of estimated daily calorie and protein requirements for ≥ 2 weeks prior to switch * Received enteral nutrition with an intact protein formula for a minimum of three days prior to a switch to a peptide-based formula * Have documentation of intolerance to an intact protein formula, followed by a switch in formula received to a peptide-based formula * Receiving a peptide-based formula formula for ≥ 2 weeks * Have documentation of an assessment of feeding tolerance following the switch * Formulas received must be indicated for use in adults.
Exclusion criteria
* Abdominal surgery (within past 30 days prior to switch) * Having any infection, including upper respiratory, viral, gastroenteritis,wound infections, c difficile, at time of switch * Having documented cow's milk protein allergy at time of switch * Medical records lacking information on rationale for switch to a peptide-based formula and/or response to change (positive, neutral or negative).
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Tube feeding interruptions | Up to 30 days after formula switch | Number of tube feeding interruptions |
| Feeding tolerance - abdominal distension/gas | Up to 30 days after formula switch | no change, tolerance improved, tolerance worsened |
| Feeding tolerance - vomiting | Up to 30 days after formula switch | no change, tolerance improved, tolerance worsened |
| Feeding tolerance - stool consistency issues | Up to 30 days after formula switch | too hard, too loose |
| Volume of formula consumed in a day vs. goal | Up to 30 days after formula switch | documentation of feeding volume after switch as less than, about the same as, or more than feeding volume achieved before switch |
| Feeding tolerance - Gastric residuals | Up to 30 days after formula switch | no change, tolerance improved, tolerance worsened |
| Feeding tolerance - gagging/retching | Up to 30 days after formula switch | no change, tolerance improved, tolerance worsened |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Medication use | Prior to and up to 30 days following formula switch. | Documented medication use |
| Caloric intake | Up to 30 days after formula switch | Measured daily calorie intake |
| Protein intake | Up to 30 days after formula switch | Measured daily protein intake |
| Weight | Prior to and up to 30 days following formula switch. | Measured body weight |
Countries
Canada
Outcome results
None listed