Perfusion
Conditions
Brief summary
This study is aimed to assess the effects of intravenously administered three fluid types on perfusion index and pulse variability index in patients during preoperative period. Patients will be randomly divided into three groups. Baseline, 5th, 10th, 15th, 20th, 25th and 30th min non-invasive blood pressure, oxygen saturation, heart rate, room temperature, perfusion index and pulse variability index will be measured and recorded.
Detailed description
Intravenous volume replacement alter the dynamics of microcirculation. Perfusion index and pulse variability index are the recent parameters to evaluate the tissue microcirculatory condition. This study is aimed to assess the effects of intravenously administered three fluid types on perfusion index and pulse variability index in patients during preoperative period. Patients will be taken to recovery room in the operating theatre and wait for 15 minutes to balance the skin temperature of the patients to the environment. Patients will be randomly divided into three groups using closed envelope technique as Group L (received 500 ml of Ringer's lactate), Group S (500 ml of saline) and Group H (received 500 ml of 6% hydroxyethylstarch). Baseline, 5th, 10th, 15th, 20th, 25th and 30th min non-invasive blood pressure, oxygen saturation, heart rate, room temperature, perfusion index and pulse variability index will be measured and recorded.
Interventions
DRUGsodium chloride
500 ml of 0.9% isotonic sodium chloride
500 ml of 6% Hydroxyethylstarch
DRUGRinger-Lactate Infusion Solution Bag
500 ml of Ringer-Lactate Infusion Solution Bag
Sponsors
Tokat Gaziosmanpasa University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* having a fasting period of 8 hours * quit smoking for 8 hours before the procedure
Exclusion criteria
* not to participate in the study * presence of peripheral vascular disease * a history of upper extremity surgery * presence of any kind of psychiatric disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Perfusion index | six months | The perfusion of the tissues |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Heart rate | six months | Heart rate |
| Blood pressure | six months | Non-invasive lood pressure |
| Oxygen saturation | six months | Blood oxygen saturation using pulse oximeter |
| Pulse variability index | six months | The intravenous fluid requirement of the tissues |
Countries
Turkey (Türkiye)
Outcome results
None listed