Magnesium Effect on Embryonal PR Interval

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03047304

Enrollment

Registered

2017-02-08

Start date

2017-02-14

Completion date

2018-03-10

Last updated

2017-02-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preterm Labor

Brief summary

Magnesium is a known treatment for neuroprotection in preterm labor before 32 week of gestation. High concentration of Magnesium in the blood stream known as cause of conduction abnormalities and ECG changes such us prolonged QT, QRS and PR in about. The goal of our work is to evaluate the PR intervals in embryos after maternal treatment with magnesium during preterm labor.

Detailed description

We will recruit 25 woman with threaten preterm labor, magnesium blood level and PR interval will be evaluated before magnesium loading dose (4gr) and 20 minutes after the loading dose. PR interval will be evaluated by Mitral-Aorta Doppler.

Interventions

DIAGNOSTIC_TESTTrans abdominal sonography

Trans abdominal sonography in order to measure fetal PR interval.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

* Women at risk for preterm labor before 32 week of gestation

Exclusion criteria

* Fetal malformations * Maternal Lupus * Fetal conduction abnormalities

Design outcomes

Primary

Measure	Time frame	Description
Prolonged PR interval	20 min after magnesium treatment	PR will be measured by Mitral-aorta doppler

Contacts

Primary ContactOla Gutzeit, MD

ola.gutzeit@gmail.com972543088220

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026