Erythermalgia
Conditions
Brief summary
Erythromelalgy (EM) is a vascular syndrome very rare affecting the feet. This disease evolve by crisis when the feet extremities become red hot and painful. There are several types of EM but this study concern the adult primitive form. For a long time, the physiopathology was not described but now we know that there is a vascular form, with microcirculatory dysfunction and a neurologic form with small fibers neuropathy. The diagnostic of neurologic form is based on clinical evaluation (DN4 questionnaire, UENS scale...) and an electromyography. Thermotest, a medical device which measure the thermic sensitivity is used to quantify neuropathy. More recently Sudoscan, a device measuring cutaneous impedance to chloride ions detect small nervous fiber in diabetic patients with good correlation with Thermotest. The purpose of this study is to analyze the vascular side and the neurologic side on patients consulting for Erythromelalgy.
Interventions
OTHERimpedance measurement and pain evaluation
Measurement of chlorine ions impedance by SUDOSCAN and pain due to temperature evaluation with THERMOTEST
Sponsors
Fondation Hôpital Saint-Joseph
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Pain with burn feeling at hands and feet extremities * Crisis activated by the heat * Age \> 18 years old
Exclusion criteria
* Patients who had burn in extremities
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of Chlorine ion production change | Day1 | patient will be measured the impedance of chlorinates ions by Sudoscan |
| Assessment of Temperature changing sensitivity | Day1 | Patients will be measured their sensitivity to temperature changing using the Thermotest |
Countries
France
Outcome results
None listed