Nutrition Disorders
Conditions
Keywords
gastric cancer, Enhanced recovery after surgery
Brief summary
This study is a prospective, single-center, randomized controlled trial. The study protocol was approved by the Ethics Committee at the First Hospital of Jilin University.The perioperation nutritional status will be assessed in gastric cancer patients within ERAS protocols.The ERAS patients were randomly divided into perioperational nutrition support group and conventional pathway group . Inter-group differences were evaluated for nutritional index,clinical recovery index, complications etc.
Interventions
PROCEDUREperioperational nutrition surpport
Oral enteral nutrition support（25 kcal/kg or 1.5 g protein/kg） for 3 days before operation
Sponsors
The First Hospital of Jilin University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* A preoperative cancer stage of T2, T3, T4, Any N, M0 without digestive obstruction confirmed by whole body CT scan, which could be treated with laparoscopic gastrectomy; * age 18-75 years; * pathologic confirmation of gastric adenocarcinoma by endoscopic biopsy; * normal hematological, renal, hepatic, and cardiac parameters,American Society of Anesthesiology (ASA) score \< III without severe systemic disease; * no history of treatment with neoadjuvant chemotherapy and/or radiotherapy * PG-SGA score ≥2，\<9
Exclusion criteria
* patients requiring conversion to open gastrectomy * excessive bleeding (˃ 500 mL);and patients opting out of the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| complication | 30 days after operation | fever；wound infection；post-operation bleeding；ileus；stenosis；leakage |
Outcome results
None listed