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Golgi Protein for HCC Diagnosis

Golgi Protein 73 for Diagnosis of HCC in Egyptian Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03039322
Enrollment
90
Registered
2017-02-01
Start date
2014-12-22
Completion date
2015-12-30
Last updated
2017-02-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Screening for Hepatocellular Carcinoma

Brief summary

This case-control study was conducted on 90 patients who were equally divided into two groups. Group 1 included 45 patients with HCV-related chronic liver disease without clinical or radiological evidence of HCC (control group), and Group 2 included 45 patients diagnosed to have HCC by Triphasic abdominal CT (patient group). Serum AFP and GP73 were measured using ELISA technique

Interventions

DIAGNOSTIC_TESTSerum Golgi Protein 73

Serum test

Sponsors

Ain Shams University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No

Inclusion criteria

* patients were older than 18 years.

Exclusion criteria

* patients with hepatic focal lesions not due to HCC such as Hemangioma, Hepatic cyst, and liver metastases; patients infected with HIV; patients with any autoimmune disease; or patients with metastatic disease.

Design outcomes

Primary

MeasureTime frame
Golgi protein correlated with presence of HCCwithin one year

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026