Knee Arthroscopy, Spinal Anesthesia
Conditions
Keywords
Local Anaesthetic, spinal anesthesia, Knee arthroscopy
Brief summary
This study compares intrathecal 1% plain chloroprocaine with intrathecal 2% hyperbaric prilocaine for patients undergoing ambulatory knee arthroscopy in terms of efficacy and side effects
Interventions
intrathecal injection of 50 mg isobaric 2-Chloroprocaine
intrathecal injection of 50 mg hyperbaric prilocaine 2%
Sponsors
Hôpital de Braine-l'Alleud
Centre Hospitalier Universitaire Saint Pierre
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anesthesiology physical status (ASA) ≤ III * Age 18-80 year * Height between 160 and 185 cm * Signed informed consent obtained prior to any study specific assessments and procedures
Exclusion criteria
* Cardiac pathology (such as Heart failure, Aortic stenosis) * Coagulation disorders (INR\>1.3, platelet \< 80 000/mm3) * Known allergy to local anaesthetics * Disagreement of the patient
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Duration of sensory block | Until complete release of sensory block | Total duration of sensory block is the interval time between the end of intrathecal injection and the complete recovery of sensory block |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Onset time of sensory block | up to 30 minutes | The levels of sensory block will be determined at 5, 10, 20 and 30 minutes after intrathecal injection. The levels of sensory block will be assessed as loss of sensation to pin-prick and cold. |
| Onset time of motor block | up to 30 minutes | The levels of motor block will be determined at 5, 10, 20 and 30 minutes after intrathecal injection. The levels of motor block will be assessed by using the Bromage Scale (0=no motor block; 1=hip blocked; 2=hip and knee blocked; 3=hip, knee, and ankle blocked). |
| Duration of motor block | Until complete regression of motor block | Total duration of motor block is the interval time between the end of intrathecal injection and the complete recovery of motor block |
| Pain assessed by Visual Analog Scale | up to 24 hours | Pain levels will be determined at the inflation of tourniquet, at the incision and every 10 minutes in the PACU (Post Anesthesia Care Unit). Visual Analog pain score (scale = 0 no pain; 10 = worst pain imaginable). |
| Side-effects (hypotension, bradycardia, urinary retention) | up to 24 hours | Assessed during and after intervention |
Countries
Belgium
Outcome results
None listed