Intrauterine Growth Restriction Asymmetrical
Conditions
Brief summary
Intrauterine growth restriction refers to a fetus that has failed to get a specific measures by a gestational age. Asymmetric type of Intrauterine growth restriction is known by normal sized head with smaller abdomen.It is important to recognize the growth restricted fetuses, because these fetuses may have fetal or neonatal complications. When blood flow is increased, the oxygen and nutrients will deliver good to the fetus. The role of low-dose aspirin therapy in management of intrauterine growth restriction is controversial. It has been used, in many studies, in prevention of intrauterine growth restriction especially in women at high risk of pre-eclampsia or obstetrical antiphospholipid syndrome.
Interventions
DRUGAspirin
This group were subjected to aspirin 75 mg once daily for 6 weeks.
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 35 Years
Healthy volunteers
No
Inclusion criteria
* The pregnant women * 28-30 weeks * Idiopathic asymmetrically intrauterine growth restriction * Middle aged women (20-35 years) * Women with abnormal umbilical artery Doppler flow indices ( \> +2 standard deviation above mean for gestational age)
Exclusion criteria
* Women less than 20 and more than 35 years * hypertensive or diabetic women * any type of smoking * multiple pregnancies * amniotic fluid index \<5 cm * premature pre-labor rupture of membranes * abnormal placenta * any fetal congenital malformations. * women had absent diastolic flow or reversed flow in umbilical artery at the time of recruitment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Estimated fetal weight | 6 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Birth weight | 6 weeks |
| Changes in Doppler blood flow indices in umbilical artery | 6 weeks |
Countries
Egypt
Outcome results
None listed