Acute Myocardial Infarction, Cerebrovascular Disease, Chronic Heart Failure, Chronic Obstructive Pulmonary Disease, Chronic Renal Failure, Diabetes Mellitus, Peripheral Vascular Disease
Conditions
Brief summary
This study aims to determine the extent to which pre-existing long-term conditions are associated with survival following a heart attack (acute myocardial infarction) using observational data from the UK's national heart attack register.
Detailed description
Using observational data from the Myocardial Ischaemia National Audit Project (MINAP) of all hospitalisations for acute myocardial infarction in all acute hospitals in England and Wales, this study aims to determine the extent to which pre-existing long-term conditions are associated with survival following acute myocardial infarction. The study will include an investigation of individual long term conditions for patients with acute myocardial infarction, including chronic heart failure, cerebrovascular disease, diabetes mellitus, chronic obstructive pulmonary disease, chronic renal failure or peripheral vascular disease as well as the combination of such conditions and their resulting impact on long term all-cause mortality (up to 8.4 years). In addition, an investigation of the association of receipt of guideline recommended care for acute myocardial infarction patients with pre-existing long term conditions will be made.
Interventions
OTHERlong term conditions
Long term conditions including diabetes mellitus, chronic obstructive pulmonary disease or asthma, chronic heart failure, chronic renal failure, cerebrovascular disease or peripheral vascular disease.
Sponsors
Marlous Hall
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients must be 18 years or older
Exclusion criteria
* Patients for which mortality data are missing
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of patients who died from any cause by the end of the study censoring period | 8.4 years | Death data was obtained from national death records from the Office for National Statistics |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of patients who received guideline recommended therapy during the study period | Any guideline therapy administered during the patients hospital admission for acute myocardial infarction, an average of 4 days | All guideline recommended therapies for acute myocardial infarction relevant to the duration of the study period (2003 to 2013) will be assessed. |
Outcome results
None listed