Ideal Sedation for Stroke Thrombectomy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03036631

Acronym

ISST

Enrollment

Registered

2017-01-30

Start date

2016-10-31

Completion date

2018-04-30

Last updated

2018-07-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic Stroke

Brief summary

The Ideal Sedation for Stroke Thrombectomy (ISST) registry will answer the key questions whether sedation with intubation and paralytics is feasible and whether it delays the time to recanalization in comparison with conscious sedation alone. As a pilot registry, it is anticipated to enroll 40 acute stroke patients requiring mechanical thrombectomy over 12-18 months. Following enrollment, data will be collected prospectively from medical records and from patients' visits.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age ≥ 18 years * Suitable for intra-arterial treatment for acute stroke up to 8 hours from onset of symptoms * Clinical equipoise for best mode of sedation

Exclusion criteria

* Any known allergy to either proposed medication and its alternative * Any patient that has been intubated prior to randomization * Posterior circulation strokes * Age ≤ 18 * Pregnant female

Design outcomes

Primary

Measure	Time frame
Time interval between groin puncture and final recanalization	6 months or at study completion

Countries

United States

Outcome results