The Effect of Tracheal Intubation on AC and DC Components of a Photoplethysmograph

The Effect of Tracheal Intubation Induced Autonomic Response on Photoplethysmography

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03032939

Enrollment

Registered

2017-01-26

Start date

2007-12-18

Completion date

2015-01-30

Last updated

2017-01-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia Intubation Complication

Brief summary

Intraoperative stress responses (vasoconstriction and changes in heart rate) and postoperative pain can be monitored using photoplethysmography (PPG). PPG measures changes in tissue volume noninvasively. Therefore it can measure acute changes in arterial diameter (vasoconstriction). PPG signal has two components, AC and DC. Effects of noxious stimuli-induced stress responses (vasoconstriction) have not been studied on the DC component of PPG. The aim of this study was to investigate the effect of a known noxious stimulus (endotracheal intubation) on both the AC and DC components of PPG.

Interventions

PROCEDUREendotracheal intubation

standard endotracheal intubation of surgical patients after induction of anesthesia

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Elective surgery * General endotracheal anesthesia * Over 18 years of age * Healthy

Exclusion criteria

* Vascular disease * Liver or kidney disease * Overweight

Design outcomes

Primary

Measure	Time frame	Description
Photoplethysmography	within 60 seconds of intubation	changes in AC and DC components of photoplethysmography

Secondary

Measure	Time frame	Description
Pulse rate	within 60 seconds of intubation	Pulse rate from photoplethysmograph

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 27, 2026